SAN FRANCISCO — A spirited Hillary Clinton took on the Trump administration Tuesday in one of her first public speeches since she lost the presidential election, criticizing the country’s Republican leaders on everything from health care to the shortage of women appointees in top administration positions.

Cracking jokes about her November defeat and her months out of the limelight since, Clinton spoke to thousands of businesswomen in San Francisco, joking there was no place she’d rather be, “other than the White House.”

Without mentioning President Donald Trump by name, Clinton faulted the Republican presidential administration repeatedly, including calling its representation of women in top jobs “the lowest in a generation.”

She rebuked White House press secretary Sean Spicer, again not by name, for hours earlier Tuesday chiding a black woman journalist during a news conference for shaking her head.

“Too many women have had a lifetime of practice taking this kind of indignity in stride,” Clinton said.

Clinton also declared herself appalled at a much-circulated photograph showing an all-male group of Republican lawmakers last month negotiating women’s coverage in health care legislation, noting a social-media parody of it that showed an all-dog panel deciding on feline care.