The Fort Pitt Museum, part of the Senator John Heinz History Center family of museums, will host a seminar from 1 to 5 p.m. April 27 commemorating the 250th anniversary of the Yellow Creek Massacre.

A news release from the museum said this thought-provoking seminar will explore the history of the Yellow Creek Massacre, a premeditated murder of approximately a dozen Iroquois people along the Ohio River about 40 miles northwest of Pittsburgh. It was carried out by about 30 local malcontents on April 30, 1774, and led by a young frontiersman named Daniel Greathouse. Known today as the Yellow Creek Massacre, it ranks as one of the most brutal atrocities committed regionally against Native Americans.

Advance registration for the seminar is encouraged. Tickets are $10 for history center members and $15 for nonmembers. Admission to the Fort Pitt Museum is included with conference registration.